Human Alanine aminotransferase 2 (GPT2) ELISA Kit

Angiopoietin-2 (Ang-2) is a secreted glycoprotein that plays a complex role in vascular development. Ang-2 contains an N-terminal coiled-coildomain, 58 - 254 amino acids (aa) and a C-terminal fibrinogen-like domain, 281 - 467 aa, that is also found in other proteins including fibrinogen, tenascin, and ficolin. Located at the N-terminus are stretches of hydrophobic residues typical of secretory signal sequences. While Ang-2 is widely expressed in the mouse embryo, it is restricted postnatally to pro-angiogenic regions including the placenta, ovaries, and uterus. Ang-2 has been implicated in cancer development due to its role in angiogenesis.Ang-2-mediated destabilization of mature vessel structures accompanied by the presence of VEGF, may contribute to the angiogenesis associated with tumor tissues.

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SPECIFICATIONS

Catalog Number

KTE62250

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

84706

Accession

Q8TD30

Additional Info

Human Alanine aminotransferase 2 (GPT2) ELISA Kit has high sensitivity and excellent specificity for detection of Human GPT2. No significant cross-reactivity or interference between Human GPT2 and analogues was observed.