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Human A/G-specific adenine DNA glycosylase (MUTYH) ELISA Kit

Cat no: KTE62225

Human A/G-specific adenine DNA glycosylase (MUTYH) ELISA Kit

MUTYH glycosylase, involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.\nMutations in the MUTYH gene cause an autosomal recessive form of familial adenomatous polyposis. Polyps caused by mutated M

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SPECIFICATIONS

Catalog Number

KTE62225

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

4595

Accession

Q9UIF7

Additional Info

Human A/G-specific adenine DNA glycosylase (MUTYH) ELISA Kit has high sensitivity and excellent specificity for detection of Human MUTYH. No significant cross-reactivity or interference between Human MUTYH and analogues was observed.

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