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Human 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase (CYP8B1) ELISA Kit

Cat no: KTE62154

Human 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase (CYP8B1) ELISA Kit

CYP8B1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. CYP8B1 is unique among the cytochrome P450 genes in that it is intronless.

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SPECIFICATIONS

Catalog Number

KTE62154

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

1582

Accession

Q9UNU6

Additional Info

Human 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase (CYP8B1) ELISA Kit has high sensitivity and excellent specificity for detection of Human CYP8B1. No significant cross-reactivity or interference between Human CYP8B1 and analogues was observed.

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