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EliKine™ Human TNF-? ELISA Kit

Cat no: KET6032

EliKine™ Human TNF-? ELISA Kit

TNFa is synthesized as a 26 kDa, type II transmembrane protein that is 233 amino acids in length. It contains a 30 amino acid (aa) cytoplasmic domain, a 26 aa transmembrane segment, and a 177 aa extracellular region. TNFa is assembled intracellularly to form a transmembrane, non-covalently-linked homotrimeric protein. The 157 aa residue soluble form of TNFa (sTNF-?is released from the C-terminus of the transmembrane protein through the activity of TNFa-converting enzyme (TACE), a membrane -bound disintegrin metalloproteinase. Rat cells known to express TNF-?include B cells, colonic columnar epithelial cells, NK and CD3 CD56 hepatic natural T cells, macrophages, monocytes and monocyte-derived dendritic cells, CD4 and CD8 T cells, mast cells, neutrophils, keratinocytes, plasma cells, and adipocytes.

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SPECIFICATIONS

Catalog Number

KET6032

Size

48T, 96T, 96T*5

Applications

ELISA

Reactivities

Hum

Gene Id

7124

Accession

P01375

Additional Info

EliKineв„ў Human TNF-? ELISA Kit has high sensitivity and excellent specificity for detection of Human TNF-?. No significant cross-reactivity or interference between Human TNF-? and analogues was observed.

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