EliKine™ Human TGF-?1 ELISA Kit

TGF-? is capable of producing a variety of effects and virtually all cell types respond to this factor in some way. The inappropriate presence of active TGF-?1 has been implicated in a variety of pathological conditions Because of the necessity for regulating its activity tightly, TGF-? is secreted by cells in the form of an inactive complex. This complex consists of TGF-?1 associated non-covalently with a protein designated the latency associated peptide (LAP). TGF-?1 and LAP represent components of a pro-peptide that is cleaved in a post-golgi compartment prior to secretion. LAP and TGF-?1 each consist of a disulfide-linked homodimer and the association of these two components renders TGF-?1 inactive and inaccessible to anti-TGF-? antibodies.\n

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SPECIFICATIONS

Catalog Number

KET6030

Size

48T, 96T, 96T*5

Applications

ELISA

Reactivities

Hum, Mouse, Rat

Gene Id

7040

Accession

P01137

Additional Info

EliKineв„ў Human TGF-?1 ELISA Kit has high sensitivity and excellent specificity for detection of Human TGF-?1. No significant cross-reactivity or interference between Human TGF-?1 and analogues was observed.