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eIF2? (phospho Ser51) Polyclonal Antibody

Cat no: ABP50305


Supplier: Abbkine Scientific Co.Ltd.
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The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha(Ernst et al., 1987 [PubMed 2948954]).
Catalogue number: ABP50305
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: ELISA, Immunofluorescence, Immunohistochemistry - fixed, Western Blot
Size: 30micro l, 100micro l, 200micro l
Accession: P05198
Gene: 1965
Concentration: 1 mg/ml
Isotype: Rabbit IgG
Clonality: Polyclonal

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