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Dnmt3b Polyclonal Antibody

Cat no: ABP51190

Dnmt3b Polyclonal Antibody

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.

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SPECIFICATIONS

Catalog Number

ABP51190

Size

30micro l, 100micro l, 200micro l

Applications

ELISA, IF, IHC-F, WB

Hosts

Rabbit

Reactivities

Hum

Gene Id

1789

Isotype

Rabbit IgG

Accession

Q9UBC3

Clonality

Polyclonal

Concentration

1 mg/ml

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