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Cleaved-PARP-1 (D214) Polyclonal Antibody

Cleaved-PARP-1 (D214) Polyclonal Antibody

Cat no: ABP50072

Supplier: Abbkine Scientific Co.Ltd.
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PARP1 encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, poly(ADP-ribose) polymerase 1 may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Catalogue number: ABP50072
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: ELISA, Immunofluorescence, Immunohistochemistry - fixed, Western Blot
Size: 30micro l, 100micro l, 200micro l
Accession: P09874
Gene: 142
Concentration: 1 mg/ml
Isotype: Rabbit IgG
Clonality: Polyclonal

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