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CA IX Monoclonal Antibody

Cat no: ABM40076

CA IX Monoclonal Antibody

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. CA9 was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.

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SPECIFICATIONS

Catalog Number

ABM40076

Size

30micro l, 100micro l, 200micro l

Applications

IF, IHC-F, IP, WB

Hosts

Mouse

Reactivities

Hum

Gene Id

768

Isotype

Mouse IgG1

Accession

Q16790

Clonality

Monoclonal

Concentration

1 mg/ml

SUPPLIER INFO

Abbkine Scientific Co.Ltd.

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