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ZMPSTE24 (zinc metallopeptidase (STE24 homolog, S. cerevisiae)) Blocking Peptide (100ug)

ZMPSTE24 (zinc metallopeptidase (STE24 homolog, S. cerevisiae)) Blocking Peptide (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-ZMPSTE24 antibody (Catalogue #: ARP46665_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP46665
Size: 100 ug
Weight: 55kDa
Gene: 10269
Format: Lyophilized powder
Target: ZMPSTE24 is a member of the peptidase M48A family. This protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in ZMPSTE24 gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.The protein encoded by this gene is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.
Alternative names: FACE-1; FACE1; FLJ14968; STE24; Ste24p
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