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ZMPSTE24 antibody - N-terminal region (ARP46665_P050)

ZMPSTE24 antibody - N-terminal region (ARP46665_P050)

This is a rabbit polyclonal antibody against ZMPSTE24. It was validated on Western Blot using a cell lysate as a positive control. Aviva Systems Biology strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (info@avivasysbio.com).

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SPECIFICATIONS

Size

50ug

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat, Bov, ZF/Fish

Format

Lyophilized powder

Presku

ARP46665_P050

Target

ZMPSTE24 is a member of the peptidase M48A family. This protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in ZMPSTE24 gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.The protein encoded by this gene is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.

Weight

55kDa

Gene Id

10269

Alternative Names

FACE-1; FACE1; FLJ14968; STE24; Ste24p; HGPS; PRO1

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