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ZIP6 Antibody (OAPB01217)

ZIP6 Antibody (OAPB01217)

The zinc transporter ZIP6, also known as SLC39A6, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP6 was initially identified as LIV-1, an estrogen-regulated gene that has been implicated in metastatic breast cancer. Elevated ZIP6 expression has also been reported in human cervical cancer and the HeLa cell line; down-regulation of ZIP6 expression in HeLa by RNAi inhibited cell proliferation, colony formation, migration and invasiveness, as well as decreasing Snail and Slug levels, suggesting ZIP6 plays a regulatory role on the ERK1/2-Snail/Slug pathway.

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SPECIFICATIONS

Size

0.1 mg

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum, Mouse

Presku

OAPB01217

Target

Solute carrier family 39 member A6

Alternative Names

ZIP6; Solute carrier family 39 member A6; Slc39A6; LIV-1

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