Reactivities: | Human, Mouse |
Presku: | AAP39212 |
Size: | 100ug |
Weight: | 60kDa |
Gene: | 16969 |
Format: | Lyophilized powder |
Target: | Zbtb7a plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals. Zbtb7a specifically represses the transcription of the CDKN2A gene. Zbtb7a efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Zbtb7a binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3'. |
Alternative names: | 9030619K07Rik; 9130006G12Rik; AI452336; FBI-1; Lrf; Pokemon; Zbtb7 |