Supplier:
Aviva Systems Biology IncorporatedZAP70 (zeta-chain (TCR) associated protein kinase 70kDa ) Blocking Peptide (the N terminal of ZAP70)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Hum
Format
Lyophilized powder
Presku
AAP61186
Target
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
Weight
34kDa
Gene Id
The peptide is characterized by mass spectroscopy
Alternative Names
FLJ17670; FLJ17679; SRK; STD; TZK; ZAP-70
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