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YWHAZ (Human) cDNA (1ug)

YWHAZ (Human) cDNA (1ug)

Supplier: Aviva Systems Biology Incorporated
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The ORF of human YWHAZ is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-YWHAZ polyclonal antibody.
Presku: ANA11204
Size: 1ug
Gene: 7534
Target: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.
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