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XRCC6 (Human) cDNA (1ug)

XRCC6 (Human) cDNA (1ug)

Supplier: Aviva Systems Biology Incorporated
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The ORF of human XRCC6 is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-XRCC6 polyclonal antibody.
Presku: ANA11438
Size: 1ug
Gene: 2547
Target: The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
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