

Supplier:
Aviva Systems Biology IncorporatedXRCC5 antibody - C-terminal region (ARP34121_T100)
Prices direct from Aviva Systems Biology Incorporated
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SPECIFICATIONS
Size
100ug
Applications
IHC, WB
Hosts
Rabbit
Reactivities
Hum, Mouse, Rat, Bov
Format
Lyophilized powder
Presku
ARP34121_T100
Target
XRCC5 encodes the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Weight
83kDa
Gene Id
7520
Alternative Names
KU80; KUB2; Ku86; NFIV; KARP1; KARP-1
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