Reactivities: | Mouse |
Presku: | AAP41307 |
Size: | 100ug |
Weight: | 36kDa |
Gene: | The peptide is characterized by mass spectroscopy |
Format: | Lyophilized powder |
Target: | Wdr5 contributes to histone modification. It may position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. It may regulate osteoblasts differentiation. |
Alternative names: | 2410008O07Rik; AA408785; AA960360; Big; Big-3 |