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VPS4B (vacuolar protein sorting 4 homolog B (S. cerevisiae) ) Blocking Peptide (the N terminal of VPS4B)(100ug)

VPS4B (vacuolar protein sorting 4 homolog B (S. cerevisiae) ) Blocking Peptide (the N terminal of VPS4B)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-VPS4B Antibody (ARP61680_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP61680
Size: 100ug
Weight: 49kDa
Gene: The peptide is characterized by mass spectroscopy
Format: Lyophilized powder
Target: The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16.
Alternative names: MIG1; SKD1; SKD1B; VPS4-2
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