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Vps36 (vacuolar protein sorting 36 (yeast) ) Blocking Peptide (the N terminal of Vps36)(100ug)

Vps36 (vacuolar protein sorting 36 (yeast) ) Blocking Peptide (the N terminal of Vps36)(100ug)


Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-Vps36 Antibody (ARP56827_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human, Mouse
Presku: AAP56827
Size: 100ug
Weight: 42kDa
Gene: The peptide is characterized by mass spectroscopy
Format: Lyophilized powder
Target: Vps36 is a component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. Binds phosphoinosides such as PtdIns(3,4,5)P3.
Alternative names: 1700010A24Rik; 2210415M20Rik; 2810408E15Rik; Eap45