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Vinculin Antibody

Vinculin Antibody

Cat no: 251810


Supplier: ABBIOTEC
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In mammalian cells, vinculin is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. Vinculin is a cytoskeletal protein associated with cell-cell and cell-matri, Xenopus/Amphibian, junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in inculin are the cause of cardiomyopathy dilated type 1W (CMD1W). Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
Catalogue number: 251810
Reactivities: Human, Mouse, Chicken/Bird, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: P18206
Antigen: Human vinculin,Porcineurified from uterus.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Mouse Monoclonal Antibody
Isotype: Mouse IgG1
Clonality: VIN-54
Additional info: Vinculin; Metavinculin; VCL