Supplier:
Aviva Systems Biology IncorporatedVDR (vitamin D (1,25- dihydroxyvitamin D3) receptor ) Blocking Peptide (the N terminal of VDR)(100ug)
Prices direct from Aviva Systems Biology Incorporated
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SPECIFICATIONS
Size
100ug
Reactivities
Hum
Format
Lyophilized powder
Presku
AAPP31933
Target
The nuclear hormone receptor for vitamin D3 also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding the same protein.
Weight
48kDa
Gene Id
The peptide is characterized by mass spectroscopy
Alternative Names
NR1I1
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