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Vasoactive Intestinal Peptide Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 250236

Vasoactive Intestinal Peptide Antibody

Vasoactive intestinal peptide (VIP) is a 28-amino-acid peptide belonging to the secretin-glucagon family of peptide hormones. Its sequence is identical in man, o, Xenopus/Amphibian,,Porcineig and rat. VIP is widely distributed in the central and peripheral nervous systems, acting as a neurotransmitter or neuromodulator. Peripherally it is involved in vaso- and bronchodilatation, smooth muscle rela, Xenopus/Amphibian,ation and stimulation of secretion. Ectopic endocrine tumors secreting VIP (VIPomas) give rise to raised plasma levels of VIP and are associated with watery diarrhea, hypokalemia and achlorhydria syndrome. VIP shows high sequence homology with peptide histidine-methionine (PHM) in man or peptide histidine-serine (PHI) in pigs or rats,Porcineresent in the same precursor, and with the neuropeptide pituitary adenylate cyclase activating polypeptide (PACAP). This antibody binds to human, bovine,Porcineorcine or rat VIP, but does not bind to PHM or PACAP.

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SPECIFICATIONS

Catalog Number

250236

Size

0.2 mg

Reactivities

Hum, Rabbit

Format

Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.

P Type

Mouse Monoclonal Antibody

Antigen

Vasoactive intestinal peptide coupled to carrier

Isotype

Mouse IgG1/k

Accession

P01282

Clonality

NA

Additional Info

VIP peptides; Vasoactive intestinal peptide

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