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UTX (ubiquitously transcribed tetratricopeptide repeat, X chromosome) Blocking Peptide (the middle region of protein) (100ug)

UTX (ubiquitously transcribed tetratricopeptide repeat, X chromosome) Blocking Peptide (the middle region of protein) (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-UTX antibody (Catalogue #: ARP39483_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP39483
Size: 100 ug
Weight: 154kDa
Gene: 7403
Format: Lyophilized powder
Target: UTX is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. UTX plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitent with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.
Alternative names: DKFZp686A03225; MGC141941; bA386N14.2
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