Home  >  Products  >  Usp10 (ubiquitin specific peptidase 10 ) Blocking Peptide (the C terminal of Usp10)(100ug)
Usp10 (ubiquitin specific peptidase 10 ) Blocking Peptide (the C terminal of Usp10)(100ug)

Usp10 (ubiquitin specific peptidase 10 ) Blocking Peptide (the C terminal of Usp10)(100ug)

Supplier: Aviva Systems Biology Incorporated
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
This is a synthetic peptide designed for use in combination with anti-Usp10 Antibody (ARP59301_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Rat
Presku: AAP59301
Size: 100ug
Weight: 87kDa
Gene: The peptide is characterized by mass spectroscopy
Format: Lyophilized powder
Target: Usp10 is a hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, SNX3 and CFTR. It acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteract MDM2 action and stabilize p53/TP53. Following DNA damage, translocates to the nucleus and deubiquitinates p53/TP53, leading to regulate the p53/TP53-dependent DNA damage response. Usp10 does not deubiquitinate MDM2 and deubiquitinates CFTR in early endosomes, enhancing its endocytic recycling.
Alternative names: MGC124997
See Full Product Listings >