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UPF2 (UPF2 regulator of nonsense transcripts homolog (yeast)) Blocking Peptide (the N terminal of UPF2)(100ug)

UPF2 (UPF2 regulator of nonsense transcripts homolog (yeast)) Blocking Peptide (the N terminal of UPF2)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-UPF2 Antibody, made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP40814
Size: 100ug
Weight: 148kDa
Gene: 26019
Format: Lyophilized powder
Target: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein.
Alternative names: DKFZp434D222; HUPF2; KIAA1408; MGC138834; MGC138835; RENT2; smg-3
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