Ultra-LEAF(TM) Purified anti-mouse Ly-6G/Ly-6C (Gr-1)

Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.

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SPECIFICATIONS

Catalog Number

108436

Size

1 mg

Applications

FC, IHC, IP, WB

Hosts

Rat

Reactivities

Mouse

Clone

RB6-8C5

Antigen

Raised against granulocytes of mouse origin

Gene Id

17067,546644

Isotype

Rat IgG2b, kappa

Clonality

Monoclonal

Dilutions

Each lot of this Ly-6G/Ly-6C antibody is quality control tested by immunofluorescent staining for flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.25 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

1 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C. This Ultra-LEAF(TM) solution contains no preservative; handle under aseptic conditions.

Alternative Names

Gr-1, Ly6G, Ly6C

Regulatory Status

RUO