Reactivities: | Human |
Presku: | AAP58971 |
Size: | 100ug |
Weight: | 53kDa |
Gene: | 25989 |
Format: | Lyophilized powder |
Target: | ULK3 is the serine/threonine protein kinase which enhances GLI1 and GLI2 transcriptional activity and consequently positively regulates GLI-dependent SHH signaling. ULK3 may exert this function by promoting GLI1 nuclear localization. ULK3 phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. |
Alternative names: | DKFZp434C131; FLJ90566 |