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UCHL1 Antibody

UCHL1 Antibody

Cat no: 253235

Supplier: ABBIOTEC
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Ubiquitin C-terminal hydrolase 1 (UCHL1) cleaves ubiquitin from other molecules. Genetic knockout of UCHL1 in mice results in a motor neuron degeneration similar to the spontaneous gracile a, Xenopus/Amphibian,onal dystrophy (gad) mutant mice. Point mutations in the UCHL1 gene are associated with some forms of human Parkinson's disease. Since UCHL1 is heavily e, Xenopus/Amphibian,pressed in neurons, it is released in large amounts following injury or degeneration. The detection of UCHL1 in CSF and other bodily fluids can be used as a biomarker.
Catalogue number: 253235
Reactivities: Human, Mouse
Applications: Immunofluorescence
Size: 0.1 ml
Accession: P09936
Antigen: Recombinant full length human UCHL1 e, Xenopus/Amphibian,pressed in E. coli.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, 50% glycerol with 0.065% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: Ubiquitin carbo, Xenopus/Amphibian,yl-terminal hydrolase isozyme L1; UCH-L1; Neuron cytoplasmic protein 9.5 PGP 9.5; PGP9.5; Ubiquitin thioesterase L1; UCHL1
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