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UBR2 (ubiquitin protein ligase E3 component n-recognin 2) Blocking Peptide (the C terminal of protein) (100ug)

UBR2 (ubiquitin protein ligase E3 component n-recognin 2) Blocking Peptide (the C terminal of protein) (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-UBR2 antibody (Catalogue #: ARP43188_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP43188
Size: 100 ug
Weight: 200kDa
Gene: 23304
Format: Lyophilized powder
Target: Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrate's destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron.Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrate's destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron (Kwon et al., 2003 [PubMed 14585983]).[supplied by OMIM].
Alternative names: C6orf133; DKFZp686C08114; KIAA0349; MGC71112; RP3-392M17.3; bA49A4.1; dJ242G1.1; dJ392M17.3
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