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UBE2L3 (ubiquitin-conjugating enzyme E2L 3) Blocking Peptide (the middle region of protein) (100ug)

UBE2L3 (ubiquitin-conjugating enzyme E2L 3) Blocking Peptide (the middle region of protein) (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-UBE2L3 antibody (Catalogue #: ARP43023_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP43023
Size: 100 ug
Weight: 18kDa
Gene: 7332
Format: Lyophilized powder
Target: UBE2L3 catalyzes the covalent attachment of ubiquitin to other proteins.It mediates the selective degradation of short-lived and abnormal proteins. UBE2L3 functions in the E6/E6-AP-induced ubiquitination of p53/TP53.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alternative names: E2-F1; L-UBC; UBCH7; UbcM4
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