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UBE2D1 (ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)) Blocking Peptide (100ug)

UBE2D1 (ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)) Blocking Peptide (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-UBE2D1 antibody (Catalogue #: ARP43006_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP42661
Size: 100 ug
Weight: 16kDa
Gene: 7321
Format: Lyophilized powder
Target: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D1 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.
Alternative names: E2(17)KB1, SFT, UBC4/5, UBCH5, UBCH5A
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