Supplier:
Aviva Systems Biology IncorporatedUBE2D1 antibody - middle region (ARP43006_T100)
Prices direct from Aviva Systems Biology Incorporated
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SPECIFICATIONS
Size
100ug
Applications
WB
Hosts
Rabbit
Reactivities
Hum, Mouse, Rat, Bov, Can, Ch/Bird, Prc, ZF/Fish
Format
Lyophilized powder
Presku
ARP43006_T100
Target
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D1 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.
Weight
16kDa
Gene Id
7321
Alternative Names
E2(17)KB1; SFT; UBC4/5; UBCH5; UBCH5A
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