Presku: | AAP58726 |
Size: | 100 ug |
Weight: | 45kDa |
Gene: | 23071 |
Format: | Lyophilized powder |
Target: | TXNDC4 mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. TXNDC4 inhibits the calcium channel activity of ITPR1. TXNDC4 may have a role in the control of oxidative protein folding in the endoplasmic reticulum. TXNDC4 is required to retain ERO1L and ERO1LB in the endoplasmic reticulum. |
Alternative names: | ERP44; KIAA0573 |