Presku: | AAP50539 |
Size: | 100 ug |
Weight: | 44kDa |
Gene: | 10641 |
Format: | Lyophilized powder |
Target: | TUSC4 suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. TUSC4 down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. TUSC4 may act as a tumor suppressor. TUSC4 suppresses cell growth and enhanced sensitivity to various anticancer drugs. |
Alternative names: | NPR2L; NPRL2 |