TUMOUR NECROSIS FACTOR ALPHA (TNFa)

TNF alpha is a potent pleiotrophic cytokine, produced by white blood cells, endothelium and several other normal and tumour cells in response to a wide variety of stimuli. TNF alpha is involved in the pathophysiological processes of several chronic and acute diseases including the induction of apoptosis and up regulation of inflammation. RANDOX recombinant TNF alpha comprises a 157 amino acid fragment (77-233) corresponding to the mature soluble TNF alpha chain protein. TNF alpha is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use.