TNFBeta is a potent multifunctional cytokine produced mainly by activated T and B lymphocytes. The protein has been shown to have a specific potent cytotoxic activity on tumour cells and a variety of other target cells as well as being a mediator of inflammation and immune function. RANDOX recombinant TNFBeta comprises a 171 amino acid fragment (35-205) corresponding to the mature TNFBeta chain protein and is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use.