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Tubulin beta-3 Antibody
ABBIOTEC

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ABBIOTEC

Cat no: 253232

Tubulin beta-3 Antibody

Tubulin is the major constituent of microtubules, e, Xenopus/Amphibian,isting as a heterodimer of the alpha and beta subunits. The beta III isoform of tubulin is found almost e, Xenopus/Amphibian,clusively in neuronal processes of adult tissues and is therefore an e, Xenopus/Amphibian,cellent marker for neurons. Neuron specific,Porcineosttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated, suggesting that they modulate the interaction of tubulin with microtubule associated proteins. Additionally, beta III tubulin has been found to be highly e, Xenopus/Amphibian,pressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy.

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SPECIFICATIONS

Catalog Number

253232

Size

0.1 ml

Applications

IHC

Reactivities

Hum, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by Protein-G affinity chromatography.

P Type

Mouse Monoclonal Antibody

Antigen

KLH-conjugated peptide encompassing a sequence within rat tubulin, beta III.

Isotype

Mouse IgG1

Accession

Q4QRB4

Clonality

AA10

Additional Info

Tubulin beta-3 chain; Neuron-specific class III beta-tubulin; Tubb3

SUPPLIER INFO

ABBIOTEC

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