Reactivities: | Mouse |
Presku: | AAP36997 |
Size: | 100ug |
Weight: | 98kDa |
Gene: | 22130 |
Format: | Lyophilized powder |
Target: | Ttf1 is a multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin.Ttf1 plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription.Ttf1 interaction with BAZ2A/TIP5 recovers DNA-binding activity. |