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Tsen15 (tRNA splicing endonuclease 15 homolog (S. cerevisiae) ) Blocking Peptide (the C terminal of Tsen15)(100ug)

Tsen15 (tRNA splicing endonuclease 15 homolog (S. cerevisiae) ) Blocking Peptide (the C terminal of Tsen15)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-Tsen15 Antibody (ARP52469_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human, Mouse
Presku: AAP52469
Size: 100ug
Weight: 18kDa
Gene: The peptide is characterized by mass spectroscopy
Format: Lyophilized powder
Target: Tsen15 is a non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3' end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3' end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.
Alternative names: 5730449L18Rik; AL023077; Sen15
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