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Trypsin CHO Human - Recombinant Human nudE Nuclear Distribution Gene E Homolog 1 (5ug)

Trypsin CHO Human - Recombinant Human nudE Nuclear Distribution Gene E Homolog 1 (5ug)

Product Introduction: NDE1 is a cytoplasmic protein which is a member of the nudE protein family. Phosphorylated during mitosis, NDE1 is critical for the formation and function of the mitotic spindle in M phase and functions to regulate the Dynein-mediated transport of kinetochore proteins, as well as centrosome duplication during interphase. NDE1 is believed to interact with NDEL1, LIS1 and Dynein IC1/2, cytosolic in a signaling pathway which regulates the formation of neurons and is fundamental to the development of the cerebral cortex.
Product Description: NDE1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 355 amino acids (1-335 a.a.) and having a molecular mass of 39.9kDa (Molecular weight on SDS-PAGE will appear higher). NDE1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

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SPECIFICATIONS

Size

5ug

Format

Sterile Filtered colorless solution.

Presku

OPPA00192

Alternative Names

Nuclear distribution protein nudE homolog 1; NudE; NDE1; NUDE; LIS4; NUDE1; HOM-TES-87.

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