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Trypsin (2C4) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 250299

Trypsin (2C4) Antibody

Trypsin is a 24 kDa enzyme of the serine proteinase family. It is produced in the pancreas as an inactive precursor, trypsinogen, but the active enzyme is located in the gastrointestinal tract where it degrades proteins to large peptides. Trypsin prefers lysine and arginine residues. One of the substrates for trypsin is chymotrypsinogen which is cleaved to produce active chymotrypsin. High levels of immunoreactive trypsin in the bloodstream can indicate pancreatic malfunction and this indicator is used to screen for and diagnose cystic fibrosis. This antibody is specific for human trypsin, trypsinogen and trypsin in comple, Xenopus/Amphibian, with alpha-1-antitrypsin and reacts weakly with bovine trypsin.

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SPECIFICATIONS

Catalog Number

250299

Size

0.1 mg

Applications

WB

Reactivities

Hum

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.

P Type

Mouse Monoclonal Antibody

Antigen

Trypsin purified from human pancreatic tissue (1)

Isotype

Mouse IgG1/k

Accession

P07477

Clonality

2C4

Additional Info

Trypsin I; Cationic trypsinogen; Serine protease 1; Beta-trypsin

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