Presku: | AAP35144 |
Size: | 100 ug |
Weight: | 106kDa |
Gene: | 7225 |
Format: | Lyophilized powder |
Target: | TRPC6 forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). |
Alternative names: | FLJ11098; FLJ14863; FSGS2; TRP6 |