Trp63 (transformation related protein 63 ) Blocking Peptide (the middle region of Trp63)(100ug)

This is a synthetic peptide designed for use in combination with anti-Trp63 Antibody (ARP33997_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

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SPECIFICATIONS

Size

100ug

Reactivities

Hum, Mouse

Format

Lyophilized powder

Presku

AAP33997

Target

This gene encodes tumor protein p63, a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include tumor proteins p53, p63, and p73, which have high sequence similarity to one another. This similarity allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. The family members can interact with each other in many ways, including direct and indirect protein interactions. This results in mutual regulation of target gene promoters. Tumor protein p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium.

Weight

50kDa

Gene Id

The peptide is characterized by mass spectroscopy

Alternative Names

AI462811; Ket; MGC115972; P51/P63; P63; P73l; Tp63; Trp53rp1