Supplier:
Aviva Systems Biology IncorporatedTrp63 (transformation related protein 63 ) Blocking Peptide (the middle region of Trp63)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Hum, Mouse
Format
Lyophilized powder
Presku
AAP33997
Target
This gene encodes tumor protein p63, a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include tumor proteins p53, p63, and p73, which have high sequence similarity to one another. This similarity allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. The family members can interact with each other in many ways, including direct and indirect protein interactions. This results in mutual regulation of target gene promoters. Tumor protein p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium.
Weight
50kDa
Gene Id
The peptide is characterized by mass spectroscopy
Alternative Names
AI462811; Ket; MGC115972; P51/P63; P63; P73l; Tp63; Trp53rp1
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