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Trim5 alpha (3B11) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252615

Trim5 alpha (3B11) Antibody

TRIM5-alpha (Tripartite motif-containing protein 5) is a protein that is found in the cells of many mammals and fends off various retrovirus infections. It protects monkeys from infection with HIV-1 and humans from infection with some other viruses. If a retrovirus has entered a cell, it needs to shed its capsid in order to reversely transcribe its genes, so that they can be e, Xenopus/Amphibian,pressed by the host cell. It is believed that TRIM5 alpha, which is present in the cytoplasm, somehow recognizes the capsid and blocks its shedding, thereby stopping the virus in its tracks. It thus represents an intracellular defense completely separate from the rest of the body's immune system.

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SPECIFICATIONS

Catalog Number

252615

Size

0.1 ml

Applications

IHC

Reactivities

Hum

Format

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of human trim5 alpha e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG1

Accession

Q9C035

Clonality

3B11H2

Additional Info

Tripartite motif-containing protein 5; RING finger protein 88; RNF88; TRIM5

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