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TPMT (thiopurine S-methyltransferase ) Blocking Peptide (the C terminal of TPMT)(100ug)

TPMT (thiopurine S-methyltransferase ) Blocking Peptide (the C terminal of TPMT)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-TPMT Antibody (ARP63262_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP63262
Size: 100ug
Weight: 27kDa
Gene: 7172
Format: Lyophilized powder
Target: This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.
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