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TOB1 (transducer of ERBB2, 1) Blocking Peptide (the middle region of TOB1)(100ug)

TOB1 (transducer of ERBB2, 1) Blocking Peptide (the middle region of TOB1)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-TOB1 Antibody(ARP52105_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP52105
Size: 100ug
Weight: 38kDa
Gene: 10140
Format: Lyophilized powder
Target: This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.
Alternative names: APRO6; MGC104792; MGC34446; PIG49; TOB; TROB; TROB1
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