Presku: | AAP42118 |
Size: | 100 ug |
Weight: | 21kDa |
Gene: | 7135 |
Format: | Lyophilized powder |
Target: | Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Each troponin-tropomyosin complex contains 1 molecule from each of the 3 troponins: T, C, and I. The troponin I (TNI) subfamily contains three genes: TNI-skeletal-fast-twitch, TNI-skeletal-slow-twitch, and TNI-cardiac. TNNI1 prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes. |
Alternative names: | DKFZp451O223, SSTNI, TNN1 |