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TNKS1BP1 (tankyrase 1 binding protein 1, 182kDa) Blocking Peptide (the middle region of protein) (100ug)

TNKS1BP1 (tankyrase 1 binding protein 1, 182kDa) Blocking Peptide (the middle region of protein) (100ug)

This is a synthetic peptide designed for use in combination with anti-TNKS1BP1 antibody (Catalogue #: ARP58347_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

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SPECIFICATIONS

Size

100 ug

Format

Lyophilized powder

Presku

AAP58347

Target

TNKS-1 mRNA in urine sediment from patients with bladder TCC correlated with tumor stage, and higher preoperative levels were associated with increased risk of early recurrence. Tankyrase-1 is required in the assembly of bipolar spindles and the spindle-pole protein NuMA as a substrate for covalent modification by tankyrase-1. Data also show that tankyrase 1 inhibition in human cancer cells enhances telomere shortening by a telomerase inhibitor and hastens cell death.

Weight

190kDa

Gene Id

85456

Alternative Names

FLJ45975; KIAA1741; TAB182

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