Reactivities: | Human |
Presku: | AAP65979 |
Size: | 100ug |
Weight: | 27kDa |
Gene: | 79931 |
Format: | Lyophilized powder |
Target: | TNIP3 binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding. |
Alternative names: | ABIN-3; FLJ21162; LIND |